College Football Picks, Schedule: Predictions Against the Spread, Odds for Top 25 Games in Week 3

After last week’s chaos that effectively turned the 2022 college football season upside down, the top 25 teams that are heavy favorites in Week 3 may be a little more cautious on Saturday. With two games between ranked opponents on the schedule and a string of top-tier non-conference games to play, there may still be plenty of hesitation before league play begins in earnest to close out September.

The most notable Saturday is the nightcap when No. 13 Miami visits No. 24 Texas A&M with the Aggies fresh off one of those aforementioned upset losses to Appalachian State. The Hurricanes are looking to flex with first-year coach Mario Cristobal, while Aggies coach Jimbo Fisher is aiming to keep his seat from getting too hot. Speaking of Cristobal, his former team appears in that other top-25 matchup when No. 25 Oregon hosts No. 12 BYU. The Cougars are feeling good after a big win at home over Baylor, while the Ducks are still looking to bounce back from a poor showing against Georgia in Week 1.

Also on the list is No. 6 Oklahoma welcoming rival Nebraska fresh off the Cornhuskers’ firing of coach Scott Frost, newly named No. 1 Georgia visiting SEC East rival South Carolina , and Auburn welcoming a tough non-conference test from No. 22 Penn State in the featured game on CBS. In other words, there will be no shortage of stories to chew on before Saturday is over.

Be sure to stick with CBS Sports around the clock for college football coverage from kickoff onward. Let’s take a look at our expert picks for the best games in week 3.

Odds via Caesars Sportsbook | All Eastern Times

No. 6 Oklahoma at Nebraska

noon | Fox, fuboTV (Free Trial) — Oklahoma hasn’t faced a Power Five foe under new coach Brent Venables. In fact, both of his wins came against teams ranked No. 95 and No. 108 on the CBS Sports 131 Rankings. While Nebraska is struggling, the jump in talent, coupled with a new direction of coaching, makes this game a bit trickier than early results would suggest. A worse Nebraska team played a better Oklahoma team within seven points last season. Since the game is taking place in Lincoln, Nebraska, don’t expect things to get out of hand. Pick: Nebraska (+11.5) — Shehan Jeyaraja

Follow Oklahoma at Nebraska live on CBS Sports.

No. 1 Georgia in South Carolina

featured game | South Carolina Gamecocks vs. Georgia Bulldogs

noon | ESPN, fuboTV (Free Trial) — South Carolina’s problems on the offensive line spell disaster in this matchup. The Gamecocks are struggling to protect quarterback Spencer Rattler and haven’t shown much running game in two games. It looks like Georgia’s defense is barely down after five players were selected in the first round of the 2022 NFL Draft, and the Bulldogs can keep South Carolina from reaching double digits. While coach Kirby Smart is unlikely to add to the scoreboard with a respected former assistant, Georgia should cover even if their offense keeps things tame. Prediction: Georgia (-24.5) –David Cobb

Follow Georgia at South Carolina live on CBS Sports.

No. 22 Penn State at Auburn

featured game | Auburn Tigers vs. Penn State Nittany Lions

15:30 | cbs, CBSSports.com, CBS Sports App While Penn State has the biggest win of the two teams, the Nittany Lions didn’t look too good on the road against Purdue. As a result, I’m not ready to trust the Nittany Lions as road favorites against Auburn, even if Auburn hasn’t inspired much confidence. The best units on the field in this matchup will be defenders, so it’s hard to imagine either team managing to get too far away from the other. That makes Auburn and points an attractive option. Prediction: Auburn (+3) –Tom Fornelli

No. 12 BYU at No. 25 Oregon

featured game | Oregon Ducks vs. BYU Cougars

15:30 | Fox, fuboTV (Free Trial) — Bottom line: BYU is better than Oregon in the vast majority of position groups. Quarterback Jaren Hall flashed his NFL arm in an upset over Baylor last weekend despite missing both of his top receiving targets. The offensive and defensive lines have excelled for most of the past three seasons. The secondary played at a high level, while running back Christopher Brooks has inserted himself very well. By contrast, Oregon has gone 1-4 in their last five FBS matchups and been outscored 201-90. With wins over Baylor, USC, Utah and four other Power Five foes last year, don’t expect the Cougars to be intimidated by Oregon’s recruiting stars. Prediction: BYU (+3.5) — Jeyaraja

UTSA at #21 in Texas

featured game | Texas Longhorns vs. UTSA Roadrunners

20:00 | Red Longhorn — This is a potential cheat game for the Longhorns, but I think they get the win. However, the status of the Hudson Card makes me hesitant to take Texas as a 12.5-point favorite. Card is at his best when he makes plays with his legs, and his ankle injury could limit that part of his game. On top of that, Jeff Traylor’s team is highly motivated against one of the Big 12’s iconic institutions. Texas gets the win, but the Roadrunners cover. Prediction: UTSA (+12.5) –Austin Nivison

No. 13 Miami at No. 24 Texas A&M

featured game | Texas A&M Aggies vs. Miami Hurricanes (FL)

21:00 | ESPN, fuboTV (Free Trial) — This will come down to a battle of quarterbacks, and the winner of that battle is clear. Tyler Van Dyke is more talented, has better protection and more weapons on the outside than Haynes King. Van Dyke and the Hurricanes offense will set the pace, resulting in this game being played in the 30s. Texas A&M won’t be able to hang on. Multiple mistakes by Texas A&M in the second half will not only give Miami coverage, but an outright victory. Prediction: Miami (+5.5) –Barrett Sallee

Which college football picks can you confidently make in Week 3 and which favorites will go down hard? Visit SportsLine to see which teams will win and cover the spread, all from a proven computer model that has generated nearly $3,400 in earnings over the past six seasons and find out.

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