Former Southwestern Conference rivals Houston and Texas Tech will meet in a non-conference game on Saturday.
The No. 25 Cougars (1-0) are in the American Athletic Conference and will join the Big 12 next season. The 1-0 Red Raiders have been in the Big 12 since 1995, the year before the SWC disbanded.
Here’s everything you need from a betting perspective on the Houston-Texas Tech game, from point spread, moneyline and total over/under (Odds via FOX Bet):
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No. 25 houston @ texas tech (4 p.m. ET, FS1)
Point difference: Texas Tech -3 (Texas Tech favorite to win by 3+ points, otherwise Houston covers)
money line: Texas Tech -162 favorites to win (bet $10 to win a total of $16.17); Houston +125 underdogs to win (bet $10 to win $22.50 total)
Total score over/under: 63.5 points scored by both teams combined

houston cougars
HOU
+3.0
+125
o63.5

Texas Tech Red Raiders
TEXT
-3.0
-161
u63.5
The Cougars and Red Raiders have met 33 times. Houston leads the all-time series 18-14-1 but Texas Tech has won nine of the last 10 games since 1991 and the last four since 2010. The Red Raiders won 38-21 in Houston last season.
Houston has won 17 straight games holding opponents under 14 points.
The Cougars have won nine straight when leading after the first quarter and 10 straight when leading at halftime.
Texas Tech is 9-1 straight (SU) and 8-2 against the spread (ATS) in the last 10 games against Houston.
The Red Raiders look to beat a Top-25 opponent for the first time since the 2019 season (No. 21 Oklahoma State, 50-44).
The Cougars rallied from a 14-point deficit for a 37-35 triple-overtime win over UTSA in Week 1, snapping the Roadrunners’ 10-game home win streak.
Texas Tech opened with a 63-10 home win over Murray State, passing for 472 yards and six touchdowns.
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