49ers vs. Broncos: How to Watch, TV, Live Stream, Odds, Prediction as Jimmy Garoppolo Takes on Russell Wilson

While they don’t play each other often, there is a bit of history between the 49ers and Broncos. The two teams met in Super Bowl XXIV in a matchup between future Hall of Fame quarterbacks Joe Montana and John Elway. San Francisco outplayed Denver that day, as the 49ers capped their dynasty by setting Super Bowl records for points scored (55) and margin of victory (45 points).

Sunday’s Week 3 matchup between the two teams promises to be significantly more competitive. Both teams come from winning after losing their first games of the season. The 49ers come to Denver after posting a 27-7 win over Seattle last Sunday. The Broncos earned their first victory of the 2022 campaign in a defensive battle with the Texans. Both teams now look to break .500 before entering the fourth week of the regular season.

We will give a preview of the game along with our prediction for the result on Sunday. This is how you can follow the action in real time.

how to look

Date: Sunday September 25 | Weather: 8:20 p.m. Eastern Time
Location: Empower Field at Mile High (Denver)
NBC | Stream: fuboTV (try for free)
To follow: CBS Sports App
Odds: 49ers -1.5, O/U 44

When the 49ers have the ball

With Trey Lance injured, Jimmy Garoppolo has resumed his role as the 49ers’ starting quarterback. Garoppolo played well in relief of Lance during last Sunday’s victory. He was 13-of-21 for 154 yards that included a touchdown pass to Ross Dwelley and a late touchdown run to freeze the game.

Deebo Samuel remains one of the focal points of the 49ers offense. An All-Pro last season, Samuel has 105 rushing yards and a touchdown this season along with 58 yards on seven receptions. Perennial Pro Bowl right wing George Kittle hopes to make his season debut on Sunday after missing the first two games with a groin injury.

The San Francisco defense will face a formidable Denver defense that currently ranks third in the NFL in points allowed. The Broncos’ defensive leaders include linebackers Bradley Chubb and Alex Singleton, defensive end Dre’Mont Jones and cornerback Patrick Surtain II. Surtain is one of 16 Broncos players on this week’s injury report, as Denver’s roster has been plagued by injuries for the opening month.

When the Broncos have the ball

The Broncos’ offense ranks 24th in the league in scoring despite ranking in the top 10 in the NFL in rushing and passing. Denver’s lack of success in the red zone is the biggest issue for the lack of scoring, as the Broncos’ offense ranks 31st in the NFL inside the opponent’s 20-yard line. The Broncos will face a 49ers defense that is a pedestrian 19th in the league in red zone efficiency.

Another reason for the Broncos’ scoring problems has been the inconsistent play of quarterback Russell Wilson, who completed less than 60% of his passes in his first two games with Denver. Wilson has developed a quick relationship with Courtland Sutton, who is second on the team in receptions and first with 194 receiving yards. The strength of the Broncos’ offense thus far has been the running back duo of Javonte Williams and Melvin Gordon. Williams is the team’s reading running back and is also Denver’s primary pass catcher. Gordon has 105 yards in two games with 4.8 yards per carry.

San Francisco represents Denver’s biggest defensive challenge yet. Like the Broncos, the 49ers have also allowed the third-lowest points allowed in the NFL for two weeks. The 49ers also boast the highest-ranked pass defense in the league and are second in the league against the run. The unit continues to be led by Nick Bosa, who has three sacks going into Sunday’s game.

featured game | Denver Broncos vs. San Francisco 49ers


The Broncos have the playmakers and defense to pull off the upset, but I’m taking on the 49ers in what should be a good game. Denver’s injuries, coupled with the 49ers’ defensive talents, should give him an edge in an otherwise even matchup. To choose: 49ers 23, Broncos 20

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